Nd functional capacity (metabolic equivalents [METs]). CPX testing was performed preoperatively

Nd functional capacity (metabolic equivalents [METs]). CPX testing was performed preoperatively, by a blinded investigator, in a standardised manner [3] with calculation of AT made by the V-slope method. NT-proBNP levels were also measured preoperatively, a level >150 pg/ml considered elevated. Results Forty-three patients were recruited, mean (SD) age 71.8 ?8.9 years. The mean (SD) AT was 10.7 ?3.2 ml/min/kg. There was no significant correlation between age and AT (r = ?.12, P = 0.45). The median level (range) of NT-proBNP was 322.8 (52?085) pg/ml. Over 85 of patients had an NT-proBNP level >150 pg/ml. There was a weak negative association betweenP194 N-terminated natriuretic propeptide type B is a better prognostic factor than MB isoenzyme of creatine kinase in patients after cardiac arrestA Samborska-Sablik, Z Sablik, W Gaszynski, J Goch, K Kula Medical University of Lodz, Poland Critical Care 2006, 10(Suppl 1):P194 (doi: 10.1186/cc4541) Background and goals The aim of our study was to assess concentrations of N-terminated propeptide type B (NTBNP), a marker of cardiac insufficiency, and MB isoenzyme of creatine kinase (CKMB), which level is adequate to the area of acute myocardial necrosis, and to compare their predictive values of survival in patients after cardiac arrest (CA). Participants Fifty-two patients after CA (CA-patients) of age 62 ?13 years. In 34 patients CA appeared during acute coronary syndrome. Twenty-six patients died after CA (CA-D), and 26 patients survived and were discharged from hospital (CA-S). Methods The state of patients after CA was assessed by scales of proven values of survival after CA used in critical care: Glasgow Coma Scale (GCS), Multiple Organ Dysfunction Score (MODS), Simplified Acute Physiology Score II (SAPS II) and Acute Physiology and Chronic Health Evaluation II (APACHE II). In CA-SAvailable online http://ccforum.com/supplements/10/STable 1 (abstract P195) Open AAA n Age (years) AT (ml/min/kg) NT-proBNP (pg/ml) 21 68.3 9.6 292 EVAR 22 74.8 11.9 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/27509597 368 0.02 <0.02 0.9 P valueNT-proBNP and AT (r = ?.24, P = 0.18). PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/21804710 Results between open repair and EVAR are summarised in Table 1. There was a positive correlation Streptolysin O between AT and METs (r = 0.41, P < 0.01). Conclusion There is no correlation between anaerobic threshold and NT-proBNP levels in patients undergoing elective abdominal aortic aneurysm repair but there was a definite positive correlation between AT and functional capacity (METs). Whether CPX or cardiac biomarkers influences outcome requires further study. References 1. Kleber FX, et al.: Eur Heart J 2004, 6:D1-D4. 2. Older P, et al.: Chest 1993, 104:663-664. 3. Doust JA, et al.: BMJ 2005, 330:625.regression using demographic parameters and parameters of inflammation (leukocytes [WBC], C-reactive protein [CRP], procalcitonin) as well as the SOFA score as independent factors. Results The mean age was 63.5 years. The mortality rate was 27 at a mean APACHE II score of 17.5. Table 1 presents individual regression coefficients if statistically significant. CRP levels did not correlate with any of the measured prohormones. Conclusions Variations in the levels of measured prohormones are only slightly affected by parameters of inflammation. However, development of organ dysfunction is well reflected by proANP and MR-proADM but only to a lesser degree by CT-proET-1.P197 Prognostic value of pro-atrial natriuretic peptide, proadrenomedullin, and pro-endothelin-1 in critically ill patientsF Bloos1, F Br.

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