Genuine Zopiclone tablets (brand names Zimovane and Imovane) is a nonbenzodiazepine hypnotic medication used in the treatment of insomnia. It is a cyclopyrrolone, which increases the normal transmission of the neurotransmitter gamma-Aminobutyric acid (GABA) in the central nervous system, and shares some pharmacological properties with the benzodiazepines.
However, Zopiclone does not bind to benzodiazepine receptors and does not affect GABA binding; instead, it binds to the omega 1 subunit of GABAA receptors. Like other hypnotic drugs, Zopiclone has both advantages and disadvantages. It increases slow wave sleep during the first half-night of sleep, but decreases delta wave deep sleep (stages 3 and 4) during the second half-night. It also decreases rapid eye movement sleep. Zopiclone hypnotic effects last six to eight hours.
The recommend dose for adults is 7.5 mg take 30 minutes before bedtime. The maximum recommended dose is 20 mg per day. Zopiclone sleeping pills should not be taken for more than 2 weeks at a time unless directed by a doctor.
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